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CA Requests Data on Bisphenol S; Lists PFOA as Carcinogen Under Prop 65

California State House

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) has selected bisphenol S (BPS) for review by the Developmental and Reproductive Toxicant Identification Committee (DARTIC) for possible listing under Proposition 65. OEHHA is initiating the development of hazard identification information on BPS and is requesting scientific information related to the reproductive toxicity of the substance. The data call-in period will end on Monday, April 18, 2022. 

OEHHA also announced that, effective February 25, 2022, perfluorooctanoic acid (PFOA) (CAS RN 335-67-1) was added to the list of chemicals known to the state to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).  OEHHA determined that PFOA met the criteria for listing under Proposition 65 based on the authoritative bodies mechanism. The basis for the listing is the National Toxicology Program (NTP) May 2020 report titled, Toxicology and Carcinogenesis Studies of Perfluorooctanoic Acid Administered in Feed to Sprague Dawley (Hsd:Sprague Dawley SD) Rats, which concluded that 2-year feeding studies provided clear evidence of PFOA’s carcinogenic activity in male rats and some evidence of carcinogenicity of PFOA in female rats. Thus far, OEHHA has not assigned a safe harbor level for the substance.