Skip to main content

FDA Adds Eight New Substances to its Inventory of Effective FCS Notifications

FDA Building

The U.S. Food and Drug Administration (FDA) recently added eight new substances to its Inventory of Effective Food Contact Substances (FCS) Notifications. The newly listed substances and the manufacturers are listed below.

(sorted Z-A)

Food Contact Substance


Effective Date


Siloxanes and silicones, di-Me, hydroxyl-terminated, reaction products with silica (CAS Reg. No. 102782-80-9).

Fuji Silysia Chemical Ltd.

Nov 25, 2016


Monochloramine (CAS Reg. No. 10599-90-3).

Buckman Laboratories, Inc.

Nov 15, 2016


Styrene-maleic anhydride copolymer, end-capped with cumene (CAS Reg. No. 26762-29-8).

Rock Paint Co., Ltd.

Nov 2, 2016


An aqueous mixture of peroxyacetic acid (PAA) (CAS Reg. No. 79-21-0), hydrogen peroxide (HP) (CAS Reg. No.7722-84- l), acetic acid (CAS Reg. No. 64-1 9-7), 1-hydroxyethylidine-1,1-diphosphonic acid (HEDP) (CAS Reg. No. 2809-21-4), and optionally sulfuric acid (CAS Reg. No. 7664-93-9).

Aquagenics Technologies

Nov 25, 2016


An aqueous mixture containing peroxyacetic acid (PAA, CAS Reg. No. 79-21-0), hydrogen peroxide (HP, CAS Reg. No. 7722-84-1), acetic acid (CAS Reg. No. 64-19-7), 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP, CAS Reg. No. 2809-21-4), and, optionally, sulfuric acid (CAS Reg. No. 7664-93-9).

PeroxyChem, LLC

Nov 30, 2016


2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene and methyl 2-methyl-2-propenoate (CAS Reg. No. 25035-81-8).

Asahi Kasei Corporation

Nov 17, 2016


1,6-Hexanediol (CAS Reg. No. 629-11-8).

The Valspar Corporation

Nov 18, 2016


Chlorine dioxide (CAS Reg. No. 10049-04-4).

Clordisys Solutions, Inc.

Nov 2, 2016


The Food and Drug Administration Modernization Act of 1997 amended the Federal Food, Drug, and Cosmetic Act to provide for the submission of food-contact notifications (FCNs). Under the FCN system, a manufacturer or supplier of a food-contact material may submit an FCN to FDA regarding the identity and use of a new food-contact substance (FCS), along with information supporting the conclusion that the substance is safe for the intended use.

If FDA does not object in writing within 120 days to the substance's use based on safety grounds, the submitter and its customers may market the substance. Once the notification becomes effective, FDA will add it to its Inventory of Effective FCS Notifications. For more background on submission of FCNs, please see the article, "What is the Best Approach to Obtaining FDA Clearance for Food Contact Substances?"