Chemical Requirements

How should migration test results be validated?

Mar 2001

Question: How should migration test results be validated?

Answer: To properly validate migration study results, the notifier should use an extract from the control sample (sample made without the test substance) or use the extract from a replicate test sample. The extracts should then be spiked, prior to work up. For non-detected analyses, the extract should be spiked at the level of detection. For detected analyses, the extract should be spiked with 1/2 times, 1 times, and 2 times the level of detection. Finally, validation analyses should be conducted in triplicate.

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